Castleman disease Cases in Radiology YouTube
Castleman disease is a rare disease of lymph nodes and related tissues. It is also known as giant lymph node hyperplasia and angiofollicular lymph node hyperplasia. It was first described by Dr. Benjamin Castleman in the 1950s 1-3. Neck involvement in Castleman disease accounts for approximately 14% of all cases of the disorder 4.
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Castleman disease is usually diagnosed by exclusion and histopathology, our patient has no history of HIV infection and shows multiple enlarged inguinal and intrabdominal lymph nodes with homogenous enhancement in the post-contrast study, no arborising calcification, the differential diagnosis includes infective, reactive causes, and neoplastic.
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Three distinct subtypes of Castleman disease have been described in literature, namely unicentric Castleman disease (UCD) human herpesvirus 8 associated multicentric Castleman disease (HHV-8-associated MCD) and idiopathic multicentric Castlema.
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Castleman disease is a non-neoplastic, non-clonal lymph node hyperplasia which can be idiopathic or associated with HIV, lymphoma, POEMS and other disorders. It commonly presents as avidly-enhancing adenopathy. Most cases (90%) are hyaline vascular, which occurs in younger patients, is unicentric, asymptomatic, and follows a benign course.
Castleman disease unicentric vascular hyaline type Image
Castleman's disease, also known as angiofollicular or benign giant lymph node hyperplasia, is an uncommon benign lymphoproliferative disorder [ 1 - 3 ]. Pathologically, two major histologic types are recognized: the hyaline-vascular type and the plasma cell type.
Castleman Disease of the Thorax Clinical, Radiologic, and Pathologic Correlation From the
Castleman disease has been associated with the human immunodeficiency virus, lymphoma, POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) syndrome, paraneoplastic pemphigus, and plasma cell dyscrasias. Aggressive forms of Castleman disease with systemic manifestations may occur.
Castleman disease. Contrastenhanced chest CT scan shows matted... Download Scientific Diagram
PURPOSE: To correlate the radiologic manifestations of thoracic Castleman disease with the clinical and histopathologic features. MATERIALS AND METHODS: The clinical, surgical, and histopathologic records; chest radiographs; and computed tomographic (CT) and magnetic resonance (MR) images in 30 pathologically proved cases of thoracic Castleman disease were reviewed. RESULTS: Patients with.
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Castleman disease in the abdomen or pelvis in the radiology literature is generally limited to case reports. The two principal histologic types of Castleman disease are hyaline-vascular and plasma cell types. A rare and potentially fatal, systemic form of Castleman disease has also been described [2]. The cytology and core his-
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Castleman disease is a rare, benign disorder of the lymph nodes that should be included in the differential diagnosis of anterior mediastinal masses. It is a lymphoproliferative disorder and is also known as angiofollicular lymph node hyperplasia, benign giant lymphoma, giant lymph node hyperplasia, and follicular lymphoreticuloma 1-3.
Castleman Disease The Great Mimic RadioGraphics
Castleman disease elevated levels of anti-VEGF Minor criteria: organomegaly ( hepatomegaly , splenomegaly , or lymphadenopathy) extravascular volume overload (edema, pleural effusion, or ascites) endocrinopathy (adrenal, thyroid, pituitary, gonadal, parathyroid, or pancreatic)
Figure 3 from Multicentric Castleman's disease manifesting in the lung clinical, radiographic
Castleman disease, also known as angiofollicular lymph node hyperplasia or giant lymph node hyperplasia, is an uncommon benign B-cell lymphoproliferative condition. It can affect several regions of the body but is commonly described as a solitary mediastinal mass. There are two distinct subtypes of Castleman disease: unicentric Castleman disease
Castleman Disease Radiology Qradiology
Castleman disease (CD), also known as giant lymph node hyperplasia, lymphoid hamartoma, or angiofollicular lymph node hyperplasia, is a group of uncommon lymphoproliferative disorders that share common lymph node histological features. The disease was first described in a single case in 1954 [ 1 ], followed by a small series of cases in 1956 [ 2 ].
Castleman disease Radiology Reference Article Radiology, Disease, Systemic
Castleman disease (CD) is a rare, nonclonal lymphoproliferative disorder having distinct subtypes depending on its etiology, pathology, and clinical presentation. It can affect lymph nodes of any body region, imitating both benign and malignant malformations, including the neck, chest, abdomen, and pelvis.
Hyaline vascular castleman disease ileocolic Image
Castleman disease (CD) is a group of rare and complex lymphoproliferative disorders that can manifest in two general forms: unicentric CD (UCD) and multicentric CD (MCD). These two forms differ in clinical manifestation, imaging appearances, treatment options, and prognosis.
Castleman Disease The Great Mimic RadioGraphics
Abstract. Castleman disease (CD) describes a group of at least 4 disorders that share a spectrum of characteristic histopathological features but have a wide range of etiologies, presentations, treatments, and outcomes. CD includes unicentric CD (UCD) and multicentric CD (MCD), the latter of which is divided into idiopathic MCD (iMCD), human.
Castleman disease Radiology Reference Article Radiology, Disease, Pleural
Unicentric Castleman disease (UCD) is considered the more common form of Castleman disease and involves one or more enlarged lymph nodes in a single region of the body that demonstrates histopathologic features that have features of Castleman disease. A subset of patients can have systemic symptoms. Location